Treatment Introduction
In recent years, the field of aesthetic medicine has witnessed a significant shift. Patients are increasingly seeking natural, regenerative treatments that deliver subtle yet effective results without the risks associated with synthetic materials.
Among these innovations, biofillers have emerged as a game-changing alternative to traditional dermal fillers, offering a safer, more holistic approach to facial rejuvenation and skin restoration.
At a glance
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Key Information
What Are Biofillers?
Biofillers are a cutting-edge treatment that uses the patient’s own biology to achieve natural, rejuvenating results. They are created from Platelet-Rich Plasma (PRP), a component of the blood rich in growth factors and regenerative properties. This PRP is combined with a specialised serum to create an injectable filler that not only smooths wrinkles and restores lost volume but also stimulates tissue regeneration and collagen production.
Unlike traditional dermal fillers, which are synthetic substances such as hyaluronic acid or poly-L-lactic acid, biofillers are autologous, meaning they are derived from the patient’s own blood. This natural composition eliminates the risk of allergic reactions or complications associated with foreign materials.


How Do Biofillers Treatment Work?
The biofiller process is straightforward and minimally invasive. It begins with a small blood sample from the patient. This blood is then processed in a centrifuge to extract the Platelet-Rich Plasma (PRP). The PRP is carefully mixed with a serum to enhance its properties, creating a filler ready for injection.
Once prepared, the biofiller is injected into targeted areas using fine needles. The treatment typically takes less than an hour, with minimal discomfort and downtime. Patients can return to their normal activities the same day. While some may experience mild swelling or redness, these effects usually subside within 24 to 48 hours.
What Areas Can Be Treated with Biofillers?
Biofillers are versatile and can be used to address a variety of aesthetic concerns. Common treatment areas include:
- Face: Enhancing facial contours, smoothing wrinkles and fine lines and restoring lost volume in areas such as the cheeks, nasolabial folds, under-eye hollows and jawline
- Hands: Rejuvenating the skin and restoring youthful volume
- Neck: Improving skin laxity and reducing the appearance of fine lines
- Elbows and knees: Treating wrinkles and sagging skin in these challenging areas
This adaptability makes biofillers a comprehensive solution for patients seeking natural, regenerative results.

Is Biofiller Right for You?
Biofillers are suitable for a wide range of patients, particularly those looking to address signs of ageing, such as fine lines, wrinkles and volume loss. They are also an excellent option for individuals seeking to rejuvenate their skin after damage caused by sun exposure or lifestyle factors.
During a personalised consultation, we assess your specific concerns and goals to determine if biofillers are the right choice for you. This tailored approach ensures that every treatment plan is designed to deliver natural, long-lasting results that enhance your unique beauty.
If you are considering a treatment that prioritises your safety, delivers natural results and supports your overall wellbeing, biofillers may be the perfect choice.
Frequently Asked Questions
How Long Does a Biofiller Treatment Take?
A biofiller treatment is a relatively quick procedure, typically taking between 30 and 60 minutes, depending on the area being treated and the amount of product required. The process involves a consultation, preparation of the biofiller material and the actual injection. Unlike some traditional fillers, biofillers derived from the patient’s own plasma may require additional preparation time. However, in most cases, the entire treatment can be completed in under an hour, making it a convenient option for those with busy schedules.
How Long Does Biofiller Last?
The longevity of biofillers varies depending on the type used, the individual’s metabolism and the area treated. Generally, biofillers last between 6 to 12 months, with some individuals experiencing results beyond this timeframe. Because biofillers stimulate collagen production, some long-term benefits can persist even after the filler itself has been broken down. Regular maintenance treatments may be required to sustain the desired results over time.
Is Biofiller Safe?
Biofillers are considered a safe option, particularly when compared to synthetic dermal fillers. Since they are often made from the patient’s own plasma (such as platelet-rich fibrin), the risk of allergic reactions or adverse side effects is significantly reduced. However, as with any injectable treatment, there are some potential risks, including bruising, swelling, or minor discomfort at the injection site. Ensuring the procedure is performed by a qualified and experienced practitioner minimises these risks.
What’s the Difference Between Biofillers and Dermal Fillers?
The primary difference between biofillers and traditional dermal fillers lies in their composition.
- Biofillers are typically derived from natural substances, such as platelet-rich fibrin (PRF) or other biocompatible materials that encourage collagen production and tissue regeneration.
- Dermal fillers are commonly made from synthetic substances like hyaluronic acid, calcium hydroxylapatite or poly-L-lactic acid. These fillers work by directly adding volume to the treated area.
While both types of fillers can be effective, biofillers are often favoured for their regenerative properties and lower risk of adverse reactions and complications.
Can Biofillers Be Dissolved?
Unlike hyaluronic acid fillers, which can be dissolved with hyaluronidase, biofillers cannot be reversed immediately after injection. However, since they are made from natural substances, they gradually break down and are absorbed by the body over time. This means that while biofillers are not instantly reversible, they do not pose long-term risks as they naturally degrade.
Can Biofiller Be Injected Into Any Area?
Biofillers can be used to enhance various areas of the face including the cheeks, tear troughs, jawline and lips. They are also effective for improving skin texture and elasticity. However, their suitability depends on the individual’s anatomy and desired results. Consulting with an experienced practitioner is essential to determine the best treatment plan for your specific needs.
What is Biofiller Downtime
Biofiller treatments generally have minimal downtime, making them a convenient option for many patients. However, the exact recovery period can depend on the individual’s response to the treatment. Here's what you can expect:
- Mild swelling and redness- Common in the first 24–48 hours, especially in sensitive areas like the lips.
- Bruising- Some patients may experience mild bruising at the injection site, which typically fades within a few days.
- Tenderness or slight discomfort- This usually resolves within a few hours to a couple of days.
- Full recovery:-Most people can return to normal activities immediately, but strenuous exercise, alcohol and excessive sun exposure should be avoided for at least 24–48 hours to minimise swelling.
Are Biofiller results immediate?
- Initial results- some volume enhancement is noticeable immediately after the procedure due to the injected material itself.
- Progressive improvement- unlike synthetic fillers that provide instant, long-lasting volume, biofillers work by stimulating the body’s natural collagen production. This means that the full effects develop gradually over a few weeks to months as collagen regeneration occurs.
- Longevity - results can last 6–12 months or longer, depending on factors like metabolism, lifestyle and the specific biofiller used.
Do Biofillers Contain Exosomes?
Some biofillers incorporate exosomes as part of their regenerative approach. Exosomes are extracellular vesicles that play a crucial role in cell communication, tissue repair and regeneration. In aesthetic medicine, exosome-enriched biofillers aim to enhance collagen production, improve skin quality and accelerate healing. These exosome-based treatments are often referred to as ExoFillers.
What is ExoFiller?
ExoFiller is a type of biofiller that includes exosomes to enhance its regenerative effects. Unlike traditional dermal fillers that primarily add volume, ExoFillers focus on stimulating the skin’s natural repair processes. They can help with:
- Collagen and elastin production, leading to firmer, more youthful skin.
- Improved skin hydration and texture, reducing fine lines and wrinkles.
- Reduced inflammation and faster healing, making them ideal for post-procedure recovery.
How Do ExoFillers Differ from Traditional Biofillers?
- Biofillers (e.g., PRF-based fillers) are typically derived from the patient’s blood, focusing on natural volumisation and gradual tissue regeneration.
- ExoFillers include exosomes derived from stem cells, offering additional regenerative properties that enhance skin health beyond simple volume restoration.
While ExoFillers are a relatively new innovation, they show promising results in anti-ageing and skin rejuvenation treatments.